A Review on External and Internal Treatment for Eli Kadi (Rat Bite) in Selected Siddha Classical Literature
Dr. Gunapriya k*1 , Dr. Thiruthani M2 , Dr. Rajarajeshwari A3
1 PG Scholar, Department of Nanju Maruthuvam, 2 Proffesor Head of the Department, Department of Nanju Maruthuvam, 3 Lecturer, Research Methodology and Biostatistics, Government Siddha Medical College, Palayamkottai, Tirunelveli, Tamilnadu, India.
* Corresponding Author
ABSTRACT
Siddha system of medicine is a unique system which has been flourished with a wide range of treatment methods and provide definite cure to vast number of diseases. The siddhars had provided us with the knowledge in the field of toxicology and provided the treatment and cure to a wide range of toxins ranging from plant biotoxins to animal biotoxins as such the bites of rats, dogs, spider, scorpion, monkey, snakes, cats etc., in the literature. According to survey report of India by NCBI, about 15 million people are bitten by animals every year and around 25000 - 30000 deaths occurs in India due to animal bites in a year. Rat bite is one among these animal bites, which encounter the rural India as victim. Not all the rat bites cause serious issues but some of the infected rat bites may cause infectious diseases like Rat-bite fever, Plaque, Hanta virus infection, Leptospirosis which may proven as fatal in the history. In this research to explore the world about the ancient Siddha management of Rat Bite. Rats are named as Eli, Mooshika which are 18 in types. This research result was recorded as; 70 plants listed as internal and external medicine by siddha management process. In internal medicine Hard paste ( Karkam), Powder (Chooranam), Decoction (kudineer), Fresh juice (Saaru) was most commonly used and externally Paste (Poochu), Nasal medication (Nassiyam) were most commonly prescribred for the management of Rat bite. The most used plant parts are Root, leaves, barks, seeds, whole plant. Treatment of rat poisoning can be given in the diseases where the source of infection is rat since the symptoms are having similarity. This research concluded as to need a clinical assessment of siddha management in modern scientific way and introducing to global level in future.
KEYWORDS: Eli kadi, Siddha Toxicology, Siddha management, External medicine, Internal medicine, Rat bite diseases.
Siddha system of medicine is a unique system which has been flourished with a wide range of treatment methods and provide definite cure to vast number of diseases. The siddhars had provided us with the knowledge in the field of toxicology as such how the toxins affect the human body and also provided the treatment and cure to a wide range of toxins ranging from plant biotoxins to animal biotoxins as such the bites of rats, dogs, spider, scorpion, monkey, snakes, cats etc., in the literature. According to survey report of India by NCBI, about 15 million people are bitten by animals every year and around 25000 - 30000 deaths occurs in India due to animal bites in a year. Rat bite is one among these animal bites, which encounter the rural India as victim. Not all the rat bites cause serious issues but some of the infected rat bites may cause infectious diseases like Rat-bite fever, Plaque, Hanta virus infection, Leptospirosis which may proven as fatal in the history.
Rats are named as Eli, Mooshika mentioned in Visha Vaithiya Sindhamani and Visha Vaithiya Aaruda Noolgal the ancient Siddha literatures. Rat are eighteen in types as per Siddha text they are Kathiri, Maniyan, Semmookkan, Valli, Kurattai, Karungkaatralaiyan, Vidaveli, Senthalaimuthi, Sevveli, Veengeli, Ularppeli, Thungeli, Pudaiyeli, Eraippeli, Sengkannan, Pulli, Kaadan, Kurungaleli. There are five modes of spread of rat (eli) poison. Semen, faeces, urine, scratches by nails and bites with teeth of rat are poisonous. Rat (eli) semen is the most poisonous and contact with this secretion can cause ill effects by the contamination in semen.
Symptoms of Rat Bite:
Fever with rigor, cough, dysnea, vitiation of blood, wheezing, lumps, pallor, arthralgia, increased body temperature, horripilation, vomiting, salivation, giddiness, loss of taste, thirst, pain at bite site, hoarseness of voice, blackish discoloration, small eruptions on the body.
Incurable Symptoms of Rat Bite:
Fainting, oedema all over the body, skin discoloration, recurrent fever, heaviness of head, excess of salivation, exudation, loss of hearing, haematemesis, urine retention, small nodules over the body resembling rat, body emitting smell of rat.
MODERN ASPECT
The Rattus genus has 64 species worldwide that make up a massive, uncountable population. Rats are from the order Rodentia which are characterized by an uncontrollable urge to gnaw. This is because the rats and others in this order have a pair of upper and lower teeth that grow nonstop, and the gnawing process files back the teeth to a manageable length. If they don’t gnaw frequently, the teeth will grow until they starve to death or are too weak to flee a predator.
Rat , (genus Rattus), the term generally denotes numerous members of several rodent families having bodies longer than about 12 cm, or 5 inches. (Smaller thin-tailed rodents are just as often referred to as mice.) The brown rat, Rattus norvegicus (also called the Norway rat), and the house rat, R. rattus (also called the black rat, ship rat, or roof rat), live virtually everywhere that human populations have settled; the house rat is predominant in warmer climates, and the brown rat dominates in temperate regions, especially urban areas. The house rat most likely originated in India.
Taxonomy
Kingdom: Animalia
Phylum: Chordata
Subphylum: Vertebrata
Class: Mammalia
Order: Rodentia
Superfamily: Muroidea
Family: Muridae
Subfamily: Murinae
Genus: Rattus
Rat Distribution:
Rats are found in all of the contiguous 48 states. They are also known to inhabit every land mass. The rat species is the most prolific invasive species worldwide.
Transmission of diseases
Mode of transmission of diseases:
Rats are an example of urban pest that transmit disease by several mechanisms, directly by contaminating food with their urine or faeces. Sometimes they transmit disease indirectly, as when fleas bite a disease infected rat, then a person or by biting people. Rat bites may cause local bacterial infection, which have good prognosis. Organisms recovered from bite wounds generally originate from the oral cavity of the biting animal, as well as from the patient's skin flora. Anaerobes have been isolated from bite wound infections, especially those associated with abscess formation.
Brown and house rat have been implicated in the spread of 40 diseases among humans, including bubonic plague, food poisoning, schistosomiasis, murine typhus, tularemia, and leptospirosis. On the other hand, the brown rat has been used in laboratories worldwide for medical, genetic, and basic biological research aimed at maintaining and improving human health. Rats are also kept as pets.
Diseases caused by rats
The common diseases that are caused by rats are:
· Hantavirus Pulmonary Syndrome
· Hemorrhagic Fever with Renal Syndrome
· Lymphocytic Chorio-meningitis (LCM)
· South American Arena viruses (Argentine hemorrhagic fever, Bolivian hemorrhagic fever, Sabiá-associated hemorrhagic fever, Venezuelan hemorrhagic fever)
Treatment:
Antibiotics such as cephalosporins or penicillinase-resistant penicillins are usually adequate for treatment of infectious complications of rat bites. Immunization against tetanus and rabies is also indicated, though rabies is rare after a rat bite. Wound management includes cleaning, debridement of tissue.
Penicillin is the treatment of choice for proven or highly suspected cases of rat bite fever. Tests of S. moniliformis antibiotic susceptibility by the disk diffusion method usually demonstrate sensitivity to penicillins, cephalosporins, carbapenems, aztreonam, clindamycin, erythromycin, nitrofurantoin, bacitracin, tetracycline, teicoplanin, and vancomycin; intermediate susceptibility to aminoglycosides, fluoroquinolones, and chloramphenicol; and resistance to trimethoprim-sulfamethoxazole, polymyxin B, and nalidixic acid.
AIM
This research work is aimed to explore the siddha management for Rat bite as per Siddha literature.
MATERIALS AND METHODS
STUDY TYPE : Literature review
REFERENCES :
From the ancient Siddha literature texts are, Sarabendrar Vaithiya Muraigal 1, Visha Vaithiya Aaruda Noolgal2, Pulippaani Vaithiyam 5003, Visha Vaithiya Sindhamani4 , Visha vaithiyam (vaithiya kalanidhi)5, Agasthiyar Mani 4000 (part 2) 6
TREATMENT OF RAT (ELI) BITE
Siddha classical literature had a wide collection of medicines ranging from herbal, herb mineral, herbometallic, herbo animal drugs to treat rat bites. Various drug preparations said in Siddha literature such as Karkam (hardpaste of drug), Kudineer (decoction), Saaru (Juice),Thailam(medicated oil), Nei(medicated ghee),Chooranam(Powder), Nasiyam(nasal medication), Poochu(paste), Kalikkam(collyrium) for rat bite.
EXTERNAL TREATMENT:
· Cauterization and blood letting from bite should be done.
· Paste of manjal (Curcuma longa), parpadagam (Mullugo cerviana) grinded with ghee should be applied on bite site.
· Paste of thagarai (Senna tora) seeds grinded with milk should be applied on bite site.
· Paste of amukkara (Withania somnifera) tuber grinded with water should be applied on bite site.
· Bark of aadhalai (Jatropha curcas) grinded with cow milk made as paste and applied on the bite site.
· Paste of pirandai (Cissus quadrangularis) should be applied on bite site.
· Leaf of vaeliparuthi (Pergularia daemia) along with latex of erukku (Calotropis gigantean) should applied on the bite site.
· Medicated oil: Ramabana Thylam external application4.
· Nasal Medication( Nasiyam):
Ø extract from the leaf of midhipagal (Momordica dioica), poondu (Allium sativum), vasambu (Acorus calamus) are used for nasal administration.
Ø Juice from paruthi (Gossypium herbaceum) leaves and gingilly oil used for nasal administration.
Ø Thurusu (Copper sulphate), seeds of azhingil (Alangium salviifolium) and murungai (Moringa oleifera), oil cake of iluppai (Madhuca longifolia), juice of lemon (Citrus limon) are used for making collyrium.
Ø Paranjodhi mai 4
Table 1. Symptomatic management of Rat Bite
|
S.NO |
SYMPTOMS OF RAT BITE |
MANAGEMENT |
TYPE OF MEDICINE |
|
1 |
Fever with rigor |
Powder of Sensanthanam (Santalum album) and Thippili (Piper longum) along with honey |
Internal |
|
2 |
Cough |
Powder of Koraikizhangu (Cyperus rotundus) with honey |
Internal |
|
3 |
Wheezing |
Hard paste of Nayuruvi (Achyranthes aspera) whole plant |
Internal |
|
4 |
Breathlessness |
Hard paste of Sankan (Azima tetracantha) root and kakkatan (Clitoria ternatea) root with milk |
Internal |
|
5 |
Bleeding gums and Toothache |
Hard paste of Avuri (Indigofera tinctoria) root with milk for 7 days |
Internal |
|
6 |
Lumps |
Powder of Perumaram (Ailanthus excelsa) bark and leaves with butter for 12 days |
Internal |
|
7 |
Increase of body temperature |
Powder of Saaranai (Trianthema portulacastrum) root with milk |
Internal |
|
8 |
Arthritic pain of limbs |
Powder of Amukkara (Withania somnifera) with honey |
Internal |
|
9 |
Paralysis of limb |
Powder of Avuri (Indigofera tinctoria) root and sankan (Azima tetracantha) root |
Internal |
|
10 |
Inflammation of the body and fever |
Hard paste of kaakattan (Clitoria ternatea) with butter milk |
Internal |
|
11 |
Oedema over the body |
Palm jaggery with 7 drops of vellerukkam (Calotropis gigantean) milk for 7 days |
Internal |
|
12 |
Swelling |
Fresh juice of Avuri |
External |
|
13 |
Blackish discoloration, patches |
Powder of Aadutheenda paalai(Aristolochia bracteolate) root and sankan (Azima tetracantha) root for 12 days |
Internal |
|
14 |
Development of tumour, Constriction of eye, Ulceration,Itching |
Powder of Chitramoolam (Plumbago zeylanica), Sivanarvembu (Indigofera aspalathoides), Kudasappaalai (Holarrhena pubescens), Vellarugu (Enicostema axillare) |
Internal |
|
15 |
Cough, Bronchitis, Congestion, Vomiting |
Hard paste of Azhingil (Alangium salviifolium) rootbark for 8 days |
Internal |
|
16 |
Halitosis |
Bark and seed of Vaazhai (Musa paradisica) grinded with honey should be given |
Internal |
|
17 |
Hematuria |
Manjal (Curcuma longa) and Parpadagam (Mullugo cerviana) grinded with ghee made as hard paste should be given |
Internal |
|
18 |
Stomatitis, Stomach ache, Toothache |
Palm jaggery with 8 drops of vellerukkam (Calotropis gigantean) milk for 7 days |
Internal |
|
19 |
Whitish discolaration of body and weakness of the body |
Powder of Vaagai (Albizia lebbeck) seeds with honey |
Internal |
|
20 |
Salivation, Burning sensation, Swelling |
Powder of Kadugu rogini (Picrorhiza kurroa) and crystal sugar |
Internal |
|
21 |
Blurring of vision |
Root of Sirukeerai (Amaranthus tricolor) along with honey |
Internal |
Table.2 List of Medicinal plants used for Rat Bite
|
S.NO |
PLANT NAME |
BOTANICAL NAME |
PART USED |
FORMULATION OF MEDICINE |
TYPE OF MEDICINE |
|
1 |
Oomathai |
Datura metel |
Leaves |
Karkam |
Internal |
|
2 |
Amukkara |
Withania somnifera |
Root |
Karkam |
Internal |
|
3 |
Pungam |
Pongamia pinnata |
Bark |
Ooral neer |
Internal |
|
4 |
Murungai |
Moringa oleifera |
Leaves |
Karkam |
Internal |
|
5 |
Naaval |
Syzygium cumini |
Root |
Ooral neer |
Internal |
|
6 |
Paavattai |
Pavetta indica |
Root |
Karkam |
Internal |
|
7 |
Peenari |
Sterculia foetida |
Bark |
Karkam |
Internal |
|
8 |
Kaakkanam |
Clitoria ternatea |
Root |
Karkam |
Internal |
|
9 |
Naralai |
Cyphostemma setosum |
Tuber |
Chooranam |
Internal |
|
10 |
Avuri |
Indigofera tinctoria |
Root |
Chooranam |
Internal |
|
11 |
Malligai |
Jasminum grandifloram |
Root |
Chooranam |
Internal |
|
12 |
Erukku |
Calotropis gigantea |
Root |
Ennai |
Internal |
|
13 |
Oomathai |
Datura metel |
Unripe fruit |
Karkam |
Internal |
|
14 |
Alinchil |
Alangium salviifolium |
Bark |
Chooranam |
Internal |
|
15 |
Kalapai kizhangu |
Gloriosa superba |
Rhizome |
Ennai |
Internal |
|
16 |
Pirkku |
Luffa acutangula |
Seed |
Ennai |
Internal |
|
17 |
Marudham |
Terminalia arjuna |
Bark |
Pongal |
Internal |
|
18 |
Sivanvembu |
Indigofera aspalathoides |
Whole plant |
Chooranam |
Internal |
|
19 |
Piraai |
Strebulus asper |
Bark |
Kudineer |
Internal |
|
20 |
Veliparuthi |
Pergularia daemia |
Root |
Karkam |
Internal |
|
21 |
Aadutheenda Paalai |
Aristolochia bracteolate |
Whole plant |
Poochu |
External |
|
22 |
Iluppai |
Madhuca longifolia |
Oil cake |
Karkam |
Internal |
|
23 |
Korai |
Cyperus Rotundus |
Rhizome |
Chooranam |
Internal |
|
24 |
Kudasapalai |
Holarrhena pubescens |
Bark |
Chooranam |
Internal |
|
25 |
Katrazhai |
Aloe vera |
Gel |
Kudineer |
Internal |
|
26 |
Sandhanam |
Santalum album |
Wood |
Karkam |
Internal |
|
27 |
Parpadagam |
Mullugo cerviana |
Whole plant |
Poochu |
Internal & External |
|
28 |
Erukku |
Calotropis gigantea |
Latex |
Karkam |
Internal |
|
29 |
Thagarai |
Senna tora |
Seed |
Karkam |
Internal |
|
30 |
Vaazhai |
Musa paradisiaca |
Fruit |
Karkam |
Internal |
|
31 |
Vaagai |
Albizia lebbeck |
Seed |
Chooranam |
Internal |
|
32 |
Punnai |
Calophyllum inophyllum |
Seed |
Chooranam |
Internal |
|
33 |
Kaatamanakku |
Jatropha curcas |
Leaves |
Karkam |
Internal |
|
34 |
Kodiveli |
Plumbago zeylanica |
Root |
Kudineer |
Internal & External |
|
35 |
Veliparuthi |
Pergularia daemia |
Leaves |
Saaru |
Internal & External |
|
36 |
Kadugurogini |
Picrorhiza kurroa |
Seed |
Chooranam |
Internal |
|
37 |
Perunkayam |
Ferula asafoetida |
Resin |
Poochu |
Internal & External |
|
38 |
Thippili |
Piper longum |
Seed |
Karkam |
Internal |
|
39 |
Chukku |
Zingiber officinale |
Rhizome |
Poochu |
External |
|
40 |
Saaranai |
Trianthema portulacastrum |
Tuber |
Chooranam |
Internal |
|
41 |
Pirandai |
Cissus quadrangularis |
Root |
Chooranam |
Internal & External |
|
42 |
Marul |
Sansevieria roxburghiana |
Tuber |
Chooranam |
Internal |
|
43 |
Karuvelampattai |
Acacia nilotica |
Bark |
Kudineer |
Internal |
|
44 |
Thavasu murungai |
Sauropus androgynus |
Leaves |
Karkam |
Internal |
|
45 |
Sirukeerai |
Amaranthus tricolor |
Root |
Karkam |
Internal |
|
46 |
Alinchil |
Alangium salviifolium |
Bark |
Poochu |
External |
|
47 |
Kuppaimeni |
Acalypha indica |
Leaves |
Poochu |
External |
|
48 |
Viizhi |
Cadaba fruticosa |
Root |
Poochu |
External |
|
49 |
Midhipagal |
Momordica dioica |
Leaves |
Saaru |
External |
|
50 |
Paruthi |
Gossypium herbaceum |
Leaves |
Ennai |
External |
|
51 |
Kovai |
Coccinia grandis |
Bark |
Karkam |
Internal |
|
52 |
Muththerukkan Sevi |
Helicteres isora |
Leaves |
Poochu |
External |
|
53 |
Uruthiratcham |
Elaeocarpus serratus |
Seed |
Karkam |
Internal |
|
54 |
Nal velai |
Cleome gynandra |
Root |
Saaru |
External |
|
55 |
Ilavangam |
Syzygium aromaticum |
Flower |
Chooranam |
Internal |
|
56 |
Aththi |
Ficus racemosa |
Leaves |
Saaru |
Internal |
|
57 |
Elumitchai |
Citrus limon |
Whole plant |
Kudineer |
Internal |
|
58 |
Vembu |
Azadirachta indica |
Seed |
Chooranam |
Internal |
|
59 |
Vellarugu |
Enicostema axillare |
Whole plant |
Chooranam |
Internal |
|
60 |
Vasambu |
Acorus calamus |
Root |
Karkam |
Internal |
|
61 |
Ulli |
Allium sativum |
Rhizome |
Karkam |
Internal |
|
62 |
Perumaram |
Ailanthus excels |
Root |
Chooranam |
Internal |
|
63 |
Sankan |
Azima tetracantha |
Root |
Karkam |
Internal |
|
64 |
Naayuruvi |
Achyranthes aspera |
Whole plant |
Chooranam |
Internal |
|
65 |
Vetrilai |
Piper betle |
Leaves |
Karkam |
Internal |
|
66 |
Seenthil |
Tinospora cordifolia |
Leaves |
Karkam |
Internal |
|
67 |
Malaiveppillai |
Melia azedarach |
Leaves |
Saaru |
Internal |
|
68 |
Palaasu |
Butea monosperma |
Leaves |
Karkam |
Internal |
|
69 |
Manjal |
Curcuma longa |
Rhizome |
Poochu |
External |
|
70 |
Vaazhai |
Musa paradisiaca |
Bark |
Saaru |
Internal |
Figure.1. TYPE OF MEDICINE
Figure. 2. PLANT PARTS USED FOR MEDICNE
Figure.3. FREQUENTLY USED PLANTS
The review showed that there are 18 types of Rat found in Siddha literature . The most common symptoms are fever, cough, breathlessness, salivation, wheezing, fainting, shivering, arthralgia, vomiting, headache, thirst, skin discolartion, swelling as per siddha text. The symptoms of rat poisoning found in siddha text is correlated with the transmission of diseases to humans caused by rat such as Leptospirosis, Rat bite fever etc. The treatment of Rat poisoning can be given in the diseases where the source of infection is rat. From this research, the result was recorded as; 70 plants listed as internal(77%) and external medicine(23%) by siddha management . In internal medicine Hard paste (Karkam), Powder ( Chooranam), Decoction (kudineer), Fresh juice (Saaru) was most commonly used and externally Paste (Poochu), Nasal medication (Nassiyam) were most commonly prescribred for the management of Rat bite. The most used plant parts are Root, leaves, barks, seeds, whole plant. From the literature the more number of treatment said in siddha text of Sarabendra vaithiya muraigal, Visha vaithiya sindhamani, Visha vaithiya aaruda noolgal.
From this research Siddha classical literature had a many therapeutic formulation ranging from herbal, herbomineral, metallic drugs to treat rat bites. This documentation will help as a reference for emergency need and management care in case of rat bite. This study also provides valuable information for further research purpose and antidote studies. Therefore this research concluded as to need a clinical assessment of siddha management in modern scientific way and introducing to global level in future.
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