Evaluation of Anti asthmatic activity of Siddha formulation, Kaagamasi thailam in eosinophilia and mast cell degranulation induced mice models
Main Article Content
Abstract
Introduction
The plant based anti-asthmatic drugs are the current need for the healthcare and current world depends on more that 80% of peoples used the herb based drug for their primary clinical needs. The present study is needed due to the gradient rise of asthmatic cases globally due to its warming, pollutions and lifestyle changes.
Methods
The anti-asthmatic and antialergic potency of the drug Kaagamasi thailam was studied using Milk induced Eosinophilia &leukocytosis and Ovalbumin induced Mast cell degranulation models in mice
Results
In the milk induced eosinophilia and leukocytosis, the drug Kaagamasi thailam showed an significant decrease in the no. of eosinophils and leukocyte count in mice models. In Ovalbumin induced study, results suggest that it prove to be a potential therapeutic agent in management of asthma and which may stabilize mast cells.
Conclusion
Kaagamasi thailam showing potent effect in animal models and reduced mast cell degranulation as well as allergic parameters.
Article Details
References
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