A Review of Toxicity Studies of Siddha Medicines in Submitted Dissertations in Siddha Post Graduate Institutions

Abstract

The Siddha system is unique in its principles, diagnosis and treatment of diseases. Since the remedy for all the ailments were foretold by the Siddhars, we are in need of scientific validation to upgrade our Siddha system globally in this modern era. A drug research starts from preclinical to clinical trials, are categorized into four phases. To enumerate the Siddha medicines that are assessed for its safety and toxicity since 2010 was taken as the primary objective of this review study. The data were collected from the submitted dissertations of Nanju Maruthuvam Department in Siddha Post Graduate Institutions. It was found that 139 Siddha Medicines were studied for its Safety and Toxicity Profile since 2010. Of 139 Siddha Medicines, Chenduram -36, Chooranam-34, Chunnum-4, Ilagam-1, Kuzhambu-1, Mathirai-25, Mezhugu-8, Parpam-28, Pathangam-2 were included. The type of animal oral toxicity studied for those Siddha medicines are Acute and Chronic toxicity studies - 61(44%), 2.Acute and Sub-acute toxicity studies-78(56%).