An Open Clinical Study on “Bala Karappan” (Atopic Dermatitis) in Children with the evaluation of Siddha Trial drug saaranai Ennai

Abstract

Siddha system of medicine has its distinctive and remarkable strength in treatingdiseases. Siddha system plays a wide ranged role in the field of pediatrics. It ensures the health of the children with its astonishing herbal formulation. Children’s health reflects the nation’s health and wealth and they are most vulnerable group in the society. Bala karappan is a common skin disorderstated as Paediatric skin disease in siddha texts which is more or less comparable with Eczema of modern paediatrics. In our classical siddha literature there are 18 types of Eczema(karappan) have been described,Signs and symptoms of eczema is nearly co releated to “Bala Karappan” mentioned in siddha system of medicine(Balavagadam). According to the siddha text it is characterized by skin rashes, papules, vesicles, pustules, fissures, oozing, ulceration,swelling,itching,hyperpigmentation lesion. The trial drug “Saaranai Ennai”(internal and external medicine) indicated for Bala Karappan is comparatively safer than synthetic drugs, this poly herbal preparation may be effective to manage Bala Karappan. The cause of balakarappan was derangement of kabam followed by vatham and pitham. The deranged kuttram is settled down by the kaippu suvai  and inipu suvai present in the trial medicine Saaranai ennai  (Internal & External medicine) there by the medicine acts as Ethirurai maruthuvam to cure the disease.Toxicological studies shows no acute and sub acute toxicity of the drug. The drug has Anti-Histamine activity.The cost of the trial medicines are low.During the clinical study no adverse events were observed. The clinical study confirms the efficacy of the trial drugs by reducing the clinical signs and symptoms like itching, Papules, Oozing and scaling. . Clinical study results found to be Good in 62.5% cases, Moderate in 25% cases, and Mild in 12.5% cases. The Clinical trial conducted in selected patients was satisfactory and encouraging.